Todacitan 1,5 mg (100 tablets) – Aflofarm

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Todacitan 1,5 mg (100 tablets) – Aflofarm

Todacitan from Aflofarm is only available in Spain with a medical prescription.

As a cheaper alternative, you can opt for Tabex from Sopharma.

Todacitan is a copycat of TABEX, choose the original product on the market since 1964

Feature Tabex Todacitan
Manufacturer Sopharma Aflofarm
Date Brought on the Market 1964 2021
Active Ingredient Cytisine Cytisine
Cost € 27,99 € 198,00
Treatment Duration 25 days 25 days


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What Todacitan is and what it is used for

Todacitan helps to stop smoking and to relieve the anxiety that occurs when you stop smoking. The goal of Todacitan treatment is the permanent cessation of smoking.

The use of Todacitan allows a gradual reduction of nicotine dependence by relieving withdrawal symptoms.

What you need to know before you use Todacitan

Do not use Todacitan:

  • if you are allergic to cytisine or any of the other ingredients of this medicine (listed in section 6),
  • if you suffer from unstable angina,
  • if you have a history of recent myocardial infarction,
  • if you suffer from clinically relevant cardiac arrhythmias,
  • if you have recently had a stroke,
  • if you are pregnant or breastfeeding.

Warnings and precautions

Talk to your doctor or pharmacist before taking Todacitan.

Todacitan should be used with caution in ischemic heart disease, heart failure, hypertension, pheochromocytoma (adrenal gland tumor), atherosclerosis (hardening of the arteries) and other peripheral vascular diseases, gastric and duodenal ulcer, gastroesophageal reflux disease, hyperthyroidism ( overactive thyroid), diabetes, schizophrenia, kidney and liver failure.

Todacitan should only be taken by people who have a firm intention to quit smoking. The use of Todacitan without stopping smoking could cause the side effects of nicotine to worsen.

Children and adolescents

Due to limited experience, the medicine is not recommended for use in children under 18 years of age.

Elderly population

Due to limited clinical experience, Todacitan is not recommended for use in patients over 65 years of age.

Patients with hepatic and renal insufficiency

There is no clinical experience with Todacitan in patients with renal or hepatic impairment; therefore, the drug is not recommended for use in such patients.

Other medicines and Todacitan

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Do not take Todacitan together with antituberculous medicines.

In some cases, as a consequence of smoking cessation (with or without Todacitan), the dose of other medicinal products may need to be adjusted. This adjustment is particularly important if you use other medicines containing theophylline (for the treatment of asthma), tacrine (for Alzheimer's disease), clozapine (for schizophrenia) or ropinirole (for the treatment of Parkinson's disease). If you are not sure, ask your doctor or pharmacist.

It is currently unknown whether Todacitan can reduce the efficacy of systemic hormonal contraceptives. If you use systemic hormonal contraceptives, you should add a second barrier method (e.g., condoms).

Pregnancy and lactation

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist before using this medicine.

If you are a woman of childbearing potential, you must use effective contraception. Ask your doctor for advice.

Todacitan is contraindicated during pregnancy and lactation.

Driving and using machines

Todacitan has no influence on the ability to drive and use machines.

Smoking cessation

The effects of changes in the body as a result of smoking cessation (with or without treatment with Todacitan) may alter the mechanism of action of other medications. Therefore, in some cases a dose adjustment may be necessary.

In some people, quitting smoking, with or without treatment, has been associated with an increased risk of experiencing changes in thinking or behavior, with feelings of depression and anxiety (including rarely suicidal ideation and suicide attempt) and may be related to worsening of the psychiatric disorder. If you have a history of a psychiatric disorder, you should discuss this with your doctor.


How to use Todacitan

Follow exactly the directions for administration of this medication given by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist again.

One package of Todacitan (100 tablets) is enough for a complete treatment. The duration of treatment is 25 days. Todacitan is for oral use and should be taken with an adequate amount of water according to the schedule below.

  • From 1st to 3rd day: 1 tablet every 2 hours (6 pills)
  • From the 4th to the 12th day: 1 tablet every 2.5 hours (5 pills)
  • From the 13th to the 16th day: 1 tablet every 3 hours (4 pills)
  • From the 17th to the 20th day: 1 tablet every 5 hours (3 pills)
  • From the 21st to the 25th day: 1-2 tablets a day (up to 2 tablets)

You must stop smoking no later than the 5th day of treatment. You should not continue to smoke during treatment because this could worsen side effects. In case of treatment failure, treatment should be stopped and may be resumed after 2 to 3 months.

If you use more Todacitan than you should

Symptoms of nicotine poisoning are observed in case of Todacitan overdose. Symptoms of overdose include, but are not limited to, malaise, nausea, vomiting, increased heart rate, blood pressure fluctuations, breathing problems, blurred vision, seizures.

If you get even one of the symptoms described or another symptom, which is not mentioned in this leaflet, stop taking Todacitan and talk to your doctor or pharmacist.

If you forget to use Todacitan

Do not take a double dose to make up for a forgotten dose.

If you stop treatment with Todacitan

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Possible adverse effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

These side effects may occur with certain frequencies, which are defined as follows:

Very common (may affect more than 1 in 10 users): changes in appetite (mainly increase), weight gain, dizziness, irritability, mood swings, anxiety, increased blood pressure (hypertension), dry mouth , diarrhea, skin rash, exhaustion, sleep disturbances (insomnia, drowsiness, lethargy, abnormal dreams, nightmares), headaches, increased heart rate, nausea, taste perversion, heartburn, constipation, vomiting, abdominal pain (especially in the upper abdomen), muscle pain.

Common (may affect 1 to 10 in 100 users): Difficulty concentrating, slow heart rate, bloating, burning tongue, feeling generally unwell.

Uncommon (affects 1 to 10 users in 1,000): feeling of heaviness in the head, decreased libido, lacrimation, dyspnea, increased sputum, excessive salivation, sweating, decreased elasticity of the skin, tiredness, increased serum transaminase levels.

Most of the side effects mentioned occur at the beginning of treatment and disappear throughout its duration. These symptoms may also be caused by stopping smoking (withdrawal symptoms) and not by treatment with Todacitan .

Communication of adverse effects

If you get any side effects, talk to your doctor or pharmacist, including possible side effects not listed in this leaflet.

More Information

Conservation of Todacitan

Keep this medicine out of the sight and reach of children.

Store below 25°C. Store in the original packaging in order to protect from light and moisture.

Do not use this medicine after the expiration date indicated on the package. The expiration date is the last day of the month indicated.

Do not dispose of any medicine down the drain or in the trash. Ask your pharmacist how to dispose of containers and medicines you no longer need. In this way, you will help protect the environment.

Contents of the container and additional information.

Composition of Todacitan

The active ingredient is cytisine. One tablet contains 1.5 mg cytisine.

The other ingredients are: mannitol, microcrystalline cellulose, magnesium stearate, glycerol dibehenate, hypromellose.

 Appearance of the product and contents of the container

Todacitan is a white, round, biconvex tablet of 6 mm diameter.

PVC/PCTFE/aluminum blisters placed in a cardboard box containing 100 tablets (4 blisters of 25 tablets each).

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